"Glee" creator Ryan Murphy and the band KINGS OF LEON do NOT get along . . . and the back-and-forth between them appears to be HEATING UP.

--Here's the latest:  Yesterday, Kings of Leon drummer NATHAN FOLLOWILL slammed Murphy on Twitter . . . saying, quote, "Dear Ryan Murphy, let it go.  See a therapist, get a manicure, buy a new bra.

--"Zip your lip, and focus on educating 7 [year]-olds how to say (eff)."

--Murphy is an openly gay man . . . so naturally, people are calling Nathan's "insults" homophobic.  And Murphy himself is among them.

--He responded, quote, "Just read [his] Tweet, in which he implied I should 'get a manicure and buy a bra.'  Wow.  That's a homophobe badly in need of some education.  I'm all for manicures, [but] don't wear a bra.

--"[I'd] guess most gay dudes don't.  But it's telling that Nathan can reduce a group of people to a mean-spirited cliché, in a time where young gay men are killing themselves all over the country because of hatred like this."

--Nathan later deleted his Tweet . . . and said he was sorry.  He Tweeted, quote, "I'm sorry 4 anyone that misconstrued my comments as homophobic or misogynistic.  I'm so not that kind of person.  I really do apologize."

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--The whole thing started when Kings of Leon refused to let "Glee" use their music.  They later said they turned it down because they weren't familiar with the show, but they also implied that by doing it they'd be "selling out."

--Then, Murphy told the "Hollywood Reporter", quote, "(Eff) you, Kings of Leon" and called them "self-centered (A-holes)," and accused them of hating on "arts education."

--Kings of Leon singer CALEB FOLLOWILL seemed STUNNED at that.  He responded, quote, "This whole 'Glee' thing is a shock to us.  It's gotten out of hand.  We're not sure where the anger is coming from."

--Bassist JARED FOLLOWILL also chimed in on Twitter . . . although it's awkwardly worded.  He said, quote, "I think I found out who I was sitting [next] to last night and he said '(Eff) You' and something about music at school.  Who gives a (crap)?"

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